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          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)

          THP-1 (人單核細胞白血病) (STR鑒定正確)

          貨號:CL-0233

          規格:1×10?cells/T25培養瓶

          價格: ¥1600

          生長培養基:RPMI-164010% FBS+0.05mM β-mercaptoethanol+1% P/S

          數量: - +

          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)
          • THP-1 (人單核細胞白血病) (STR鑒定正確)

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          THP-1 (人單核細胞白血病) (STR鑒定正確) ¥1600

          細胞培養最優解!

          套餐組合價:¥2050¥2150

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          產品概述
          產品信息
          名稱 THP-1 (人單核細胞白血病) (STR鑒定正確)
          別稱 THP1; THP 1; THPI; THP-1(ATCC); Tohoku Hospital Pediatrics-1
          種屬
          生長特性 懸浮細胞
          細胞形態 單核細胞
          生長培養基 RPMI-164010% FBS+0.05mM β-mercaptoethanol+1% P/S
          凍存條件 凍存液:55% 基礎培養基+40%FBS+5%DMSO 溫度:液氮
          培養條件 氣相:空氣,95%;CO2,5% 溫度:37℃
          推薦傳代比例 5×10^5-1×10^6cells/mL
          推薦換液頻率 2~3次/周
          注意事項 該細胞為懸浮細胞,請注意離心收集細胞懸液;請勿直接倒掉細胞培養液。
          參考資料(來源文獻)
          背景描述 THP-1細胞對乳汁珠和激活的紅細胞有吞噬作用,無表面和胞質免疫球蛋白。THP-1細胞可以用佛波醇、TPA誘導單核細胞分化。
          年齡(性別)
          組織來源 急性單核細胞白血病,單核細胞
          細胞類型 腫瘤細胞
          腫瘤類型 白血病細胞
          生物安全等級 1
          倍增時間 ~36-72 hours
          受體表達情況 complement (C3), expressed;Fc, expressed
          抗原表達情況 HLA A2, A9, B5, DRw1, DRw2
          基因表達情況 lysozyme, HLA A2, A9, B5, DRw1, DRw2
          保藏機構 ATCC; TIB-202 DSMZ; ACC-16 ECACC; 88081201
          STR鑒定
          • STR位點信息
            Amelogenin X,Y
            CSF1PO 11,13
            D2S1338 17,18
            D3S1358 15,17
            D5S818 11,12
            D7S820 10
            D8S1179 10,14
            D13S317 13
            D16S539 11,12
            D18S51 13,14
            D19S433 12.2,13
            D21S11 30,31.2
            FGA 24,25
            PentaD 10,12
            PentaE 11,15
            TH01 8,9.3
            TPOX 8,11
            vWA 16
            D6S1043 14
            D12S391 19
            D2S441 10,11
          • STR鑒定圖
          參考文獻
          文獻列表
          • Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles(2022/08/23)

            作者:YangLin Wu, Chenhui Zhang, Yun Teng

            期刊:Military Medical Research

            DOI:10.1186/s40779-022-00404-0

            影響因子 :21.200

            引用產品:CL-0233 PM150110

          • Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model(2023/03/06)

            作者:Daogong Zhang, Wenqian Yu, Jiahui Liu

            期刊:Nature Communications

            DOI:10.1038/s41467-023-36949-4

            影響因子 :16.600

            引用產品:CL-0005 CL-0233

          • Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype(2023/03/31)

            作者:Xinhua Wu, Yangyang He, Zhangrong Chen

            期刊:Nature Communications

            DOI:10.1038/s41467-023-37527-4

            影響因子 :16.600

            引用產品:CL-0129 CL-0190 CL-0233

          • Water-extracted Lonicera japonica polysaccharide attenuates allergic rhinitis by regulating NLRP3-IL-17 signaling axis(2022/09/03)

            作者:Xinyu Bai, Ping Liu, Hengyan Shen

            期刊:CARBOHYDRATE POLYMERS

            DOI:10.1016/j.carbpol.2022.120053

            影響因子 :11.200

            引用產品:CL-0233 CM-0233

          • Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer(2022/12/10)

            作者:Xiaoyan Yang, Jinguo Zhang, Qiaomei Zhou

            期刊:JOURNAL OF NANOBIOTECHNOLOGY

            DOI:10.1186/s12951-022-01738-6

            影響因子 :10.200

            引用產品:CL-0007 CL-0029 CL-0042 CL-0233 CL-0341

          • The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation(2022/03/09)

            作者:Yanglin Wu,Yun Teng, Chenhui Zhang

            期刊:Journal Of Nanobiotechnology

            DOI:10.1186/s12951-022-01320-0

            影響因子 :10.200

            引用產品:CL-0233 PM150110

          • HIMF deletion ameliorates acute myocardial ischemic injury by promoting macrophage transformation to reparative subtype(2021/04/23)

            作者:Yanjiao Li, Min Dong, Qing Wang

            期刊:Basic Research in Cardiology

            DOI:10.1007/s00395-021-00867-7

            影響因子 :9.500

            引用產品:CL-0233

          • ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression(2022/08/01)

            作者:Yu You, Diguang Wen, Lu Zeng

            期刊:International Journal of Biological Sciences

            DOI:10.7150/ijbs.70149

            影響因子 :9.200

            引用產品:CL-0102 CL-0103 CL-0120 CL-0212 CL-0233 CL-0341

          • SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma(2022/12/24)

            作者:Liying Han, Jinpeng Zhou, Leiyang Li

            期刊:Cell Death & Disease

            DOI:10.1038/s41419-022-05526-w

            影響因子 :9.000

            引用產品:CL-0233 CL-0238 CL-0578 CL-0583

          • Exosomal transfer of tumor-associated macrophage-derived hsa_circ_0001610 reduces radiosensitivity in endometrial cancer(2021/08/30)

            作者:Xiaobin Gu, Yonggang Shi, Meilian Dong

            期刊:Cell Death & Disease

            DOI:10.1038/s41419-021-04087-8

            影響因子 :9.000

            引用產品:CL-0100 CL-0233 CL-0283

          • DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation(2021/09/21)

            作者:Tanjing Song, Qingli Zou, Yingying Yan

            期刊:Cell Reports

            DOI:10.1016/j.celrep.2021.109739

            影響因子 :8.800

            引用產品:CL-0233 CL-0572 PM150110 PM150510

          • Fucoidan-loaded, neutrophil membrane-coated nanoparticles facilitate MRSA-accompanied wound healing(2023/02/18)

            作者:Jingyi Li, Jiahao Wang, Zhen Zhang

            期刊:MATERIALS & DESIGN

            DOI:10.1016/j.matdes.2023.111758

            影響因子 :8.400

            引用產品:CL-0172 CL-0190 CL-0233

          • Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration(2023/03/13)

            作者:Weiming Zhao, Lan Wang, Juntang Yang

            期刊:Cell Communication and Signaling

            DOI:10.1186/s12964-023-01040-4

            影響因子 :8.400

            引用產品:CL-0233 PM150110

          • Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages(2021/04/20)

            作者:Zhongwei Luo, Kun Xia, Yiwei Liu

            期刊:International Journal of Nanomedicine

            DOI:10.2147/IJN.S304515

            影響因子 :8.000

            引用產品:CL-0190 CL-0233

          • MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses(2022/03/12)

            作者: JiajieTu, Yilong Fang, Dafei Han

            期刊:Oncogene

            DOI:10.1038/s41388-022-02236-7

            影響因子 :8.000

            引用產品:CL-0233 CL-0237 CL-0238

          • Human Keratinocyte-Derived Exosomal MALAT1 Promotes Diabetic Wound Healing by Upregulating MFGE8 via microRNA-1914-3p(2023/02/20)

            作者:Liwen Kuang, Chenchen Zhang, Binghui Li

            期刊:International Journal of Nanomedicine

            DOI:10.2147/IJN.S399785

            影響因子 :8.000

            引用產品:CL-0005 CL-0233

          • Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages(2023/03/21)

            作者:Guofu Hu, Zihui Yuan, Jian Wang

            期刊:BIOMEDICINE & PHARMACOTHERAPY

            DOI:10.1016/j.biopha.2023.114333

            影響因子 :7.500

            引用產品:CL-0233

          • Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma(2022/08/11)

            作者:Jichang Liu, Hongchang Shen, Wenchao Gu

            期刊:Frontiers in Immunology

            DOI:10.3389/fimmu.2022.960738

            影響因子 :7.300

            引用產品:CL-0016 CL-0233 CL-0668

          • Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes(2022/04/04)

            作者:Jiannan Zhao, Yongling Li, Jing Ma, Jingting Liu

            期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

            DOI:10.1016/j.ejmech.2022.114338

            影響因子 :6.700

            引用產品:CL-0233

          • C/EBPβ is a key transcription factor of ox-LDL inducing THP-1 cells to release multiple pro-inflammatory cytokines(2021/10/04)

            作者:Jun Ma, Xiangyu Yang, Xiaoping Chen

            期刊:Inflammation Research

            DOI:10.1007/s00011-021-01509-3

            影響因子 :6.700

            引用產品:CL-0233

          • Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis(2023/01/23)

            作者:Jun Yang, Minxiu Wang, Yulan Xu

            期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

            DOI:10.1016/j.ejmech.2023.115144

            影響因子 :6.700

            引用產品:CL-0233 CL-0370 CL-0560

          • WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization(2023/04/03)

            作者:Yanhui Bai, Xiaohang Jiao, Jinge Hu

            期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

            DOI:10.1016/j.bbadis.2023.166708

            影響因子 :6.200

            引用產品:CL-0233

          • Sennoside A is a novel inhibitor targeting caspase-1(2022/09/01)

            作者:Jiasi Wu, Yuejia Lan, Xiaoke Shi

            期刊:Food & Function

            DOI:10.1039/D2FO01730J

            影響因子 :6.100

            引用產品:CL-0190 CL-0233

          • SQSTM1/p62 Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma(2023/04/25)

            作者:Jinghua Lu, Yipei Ding, Wanqiu Zhang

            期刊:Cells

            DOI:10.3390/cells12091238

            影響因子 :6.000

            引用產品:CL-0233

          • Single-cell transcriptome analysis reveals aberrant stromal cells and heterogeneous endothelial cells in alcohol-induced osteonecrosis of the femoral head(2022/04/06)

            作者:Liao Zheting, Jin Yu, Chu Yuhao

            期刊:Communications Biology

            DOI:10.1038/s42003-022-03271-6

            影響因子 :5.900

            引用產品:CL-0137 CL-0233 CM-0233

          • 1,25(OH)2D3 Promotes Macrophage Efferocytosis Partly by Upregulating ASAP2 Transcription via the VDR-Bound Enhancer Region and ASAP2 May Affect Antiviral Immunity(2022/11/21)

            作者:Hui Shi, Jiangling Duan, Jiayu Wang, Haohao Li, Zhiheng Wu, Shuaideng Wang, Xueyan Wu, Ming Lu

            期刊:Nutrients

            DOI:10.3390/nu14224935

            影響因子 :5.900

            引用產品:CL-0233 CL-0370

          • Lactate from glycolysis regulates inflammatory macrophage polarization in breast cancer(2023/02/02)

            作者:Chao Wang, Linxuan Xue, Wenqiang Zhu

            期刊:CANCER IMMUNOLOGY IMMUNOTHERAPY

            DOI:10.1007/s00262-023-03382-x

            影響因子 :5.800

            引用產品:CL-0233

          • Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia(2023/02/17)

            作者:Ziyao Ou, Ke Wang, Wenwen Shen

            期刊:BIOCHEMICAL PHARMACOLOGY

            DOI:10.1016/j.bcp.2023.115458

            影響因子 :5.800

            引用產品:CL-0233 CL-0572

          • Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4(2022/10/20)

            作者:Hongfei Liu, Jiankun Liu, Changkun Long

            期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

            DOI:10.3390/ijms232012627

            影響因子 :5.600

            引用產品:CL-0233

          • Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD.(2023/03/10)

            作者:Pengbei Fan, Yige Zhang, Shenao Ding

            期刊:Frontiers in Pharmacology

            DOI:10.3389/fphar.2023.1139137

            影響因子 :5.600

            引用產品:CL-0233

          • Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway(2023/04/15)

            作者:Yani He, Yuting Wang, Xiangbin Jia

            期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

            DOI:10.1016/j.intimp.2023.110192

            影響因子 :5.600

            引用產品:CL-0190 CL-0233

          • Inhibiting vascular smooth muscle cell proliferation mediated by osteopontin via regulating gut microbial lipopolysaccharide: A novel mechanism for paeonol in atherosclerosis treatment(2022/08/11)

            作者:Xiaoyan Shi, Hongfei Wu, Yarong Liu

            期刊:Frontiers in Pharmacology

            DOI:10.3389/fphar.2022.936677

            影響因子 :5.600

            引用產品:CL-0233

          • Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB(2023/02/27)

            作者:Haiyang Yu, Jing Pan, Siyue Zheng

            期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

            DOI:10.3390/ijms24054593

            影響因子 :5.600

            引用產品:CL-0233

          • Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE?/? Mice by Regulating PPARγ/FAK Signaling Pathway(2020/04/22)

            作者:Jianan Geng, Wenwen Fu, Xiaofeng Yu

            期刊:Frontiers in Pharmacology

            DOI:10.3389/fphar.2020.00500

            影響因子 :5.600

            引用產品:CL-0122 CL-0233

          • Systematic analysis of lysine crotonylation in human macrophages responding to MRSA infection(2023/02/08)

            作者:Hao Zhang, Wei Ma, Haoru Liu

            期刊:Frontiers in Cellular and Infection Microbiology

            DOI:10.3389/fcimb.2023.1126350

            影響因子 :5.500

            引用產品:CL-0233

          • RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)

            作者:Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong

            期刊:CNS Neuroscience & Therapeutics

            DOI:10.1111/cns.14031

            影響因子 :5.500

            引用產品:CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122

          • Advanced glycation end products reduce macrophage‐mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation(2020/07/15)

            作者:Xiaoying Xie, Chuan Yang, Chaohui Duan

            期刊:European Journal Of Immunology

            DOI:10.1002/eji.201948477

            影響因子 :5.400

            引用產品:CL-0233

          • Neuropeptide Y regulates cholesterol uptake and efflux in macrophages and promotes foam cell formation(2022/09/29)

            作者:Yu Cai, Zhengchao Wang, Lun Li

            期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

            DOI:10.1111/jcmm.17561

            影響因子 :5.300

            引用產品:CL-0233

          • Negative feedback loop of ERK/CREB/miR‐212‐3p inhibits HBeAg‐induced macrophage activation(2020/08/07)

            作者:Wenjun Chen, Hongjun Bian, Xiaoyu Xie

            期刊:Journal Of Cellular And Molecular Medicine

            DOI:10.1111/jcmm.15723

            影響因子 :5.300

            引用產品:CL-0233

          • miR‐129‐2‐3p directly targets SYK gene and associates with the risk of ischaemic stroke in a Chinese population(2018/11/29)

            作者:Suli Huang, Ziquan Lv, Ying Wen

            期刊:Journal Of Cellular And Molecular Medicine

            DOI:10.1111/jcmm.13901

            影響因子 :5.300

            引用產品:CL-0005 CL-0122 CL-0233 CL-0239

          • Sirt4 deficiency promotes the development of atherosclerosis by activating the NF-κB/IκB/CXCL2/3 pathway(2023/04/21)

            作者:Shuting Chang, Guanzhao Zhang, Lanlan Li

            期刊:ATHEROSCLEROSIS

            DOI:10.1016/j.atherosclerosis.2023.04.006

            影響因子 :5.300

            引用產品:CL-0233

          • Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis(2023/01/23)

            作者:Shuai Zhang, Yu Sun, Qi Xiao

            期刊:MOLECULAR NEUROBIOLOGY

            DOI:10.1007/s12035-023-03214-0

            影響因子 :5.100

            引用產品:CL-0233

          • ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury(2022/03/10)

            作者:Zhen Yu, Xiaoyu Xie, Xiaonan Su

            期刊:Cellular Signalling

            DOI:10.1016/j.cellsig.2022.110304

            影響因子 :4.800

            引用產品:CL-0233

          • α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously(2023/02/22)

            作者:Yijin Wu, Sasa Zhang, Qin Yin

            期刊:Drug Design Development and Therapy

            DOI:10.2147/DDDT.S397914

            影響因子 :4.800

            引用產品:CL-0233

          • Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms(2022/08/31)

            作者:Hesuyuan Huang, Xuyang Ding, Dan Xing

            期刊:MOLECULES

            DOI:10.3390/molecules27175619

            影響因子 :4.600

            引用產品:CL-0233

          • lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway(2022/10/13)

            作者:Yuanxiu Gan, Jie Long, Yan Zeng

            期刊:MEDIATORS OF INFLAMMATION

            DOI:10.1155/2022/9923204

            影響因子 :4.600

            引用產品:CL-0233

          • Quantitative Proteomic Analysis Reveals the Mechanisms of Sinapine Alleviate Macrophage Foaming(2023/02/21)

            作者:Aiyang Liu, Bin Liao, Shipeng Yin

            期刊:MOLECULES

            DOI:10.3390/molecules28052012

            影響因子 :4.600

            引用產品:CL-0233

          • Extracellular vesicles derived from hypoxia-preconditioned bone marrow mesenchymal stem cells ameliorate lower limb ischemia by delivering miR-34c(2023/02/02)

            作者:Xitao Peng, Junhua Liu, Lijun Ren

            期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY

            DOI:10.1007/s11010-023-04666-7

            影響因子 :4.300

            引用產品:CL-0233 CL-0675 CM-0675 CP-H166

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